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Preparation and Filtration of LVP

For mass-production, the batch size should be according to GMP requirement in selection of preparation tank. Normally, 0.5T concentration tank matches 2.5T dilution tank.
There must be pre-filter to remove pyrogen-adhering active carbon in the titanic filtering system.
Pre-filtration in dilution system is for particle-removing and prolonging final filter's life. Final filtration is for decreasing bio-burden or bacteria-removing before final sterilizing.
Pre-filtration is for colloid and particle removing, prolong the final filter's life. For sugar, salt and water solution, pre-filtration is for particle-removing, so recycle flow could be adopted. For amino protein or other nutrition liquid, pre-filtering is for decreasing bio-burden, and bacteria-removing before final sterilizing.
Application: For ensuring steady final packing, selection of suitable filters affects the filtering system cost directly. The filter's structure will affect the reliability and durability. It must stand steam sterilizing.
Breathing filtration is for bacteria and virus removing ( 0.22um ).

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